Correction for Ding et al., Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles.
نویسندگان
چکیده
MICROBIOLOGY Correction for “Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles,” by Qiang Ding, Brigitte Heller, Juan M. V. Capuccino, Bokai Song, Ila Nimgaonkar, Gabriela Hrebikova, Jorge E. Contreras, and Alexander Ploss, which appeared in issue 5, January 31, 2017, of Proc Natl Acad Sci USA (114:1147–1152; first published January 17, 2017; 10.1073/pnas.1614955114). The authors wish to note the following: “It has been brought to our attention that the original Fig. 5A in our paper contained a duplicate image in which the panel showing the localization of ORF3 86-88A mutant was duplicated and also shown as ORF3 95-97A mutant. In the corrected version of Fig. 5A shown below, we have replaced the duplicate image with the correct original data. After careful reexamination of the original data, we are confident that the error in assembling this figure does not affect the validity of the research or the conclusions that we have drawn. We are grateful to the careful reader who brought this mistake to our attention and apologize for any confusion that this error may have caused.” The corrected Fig. 5 and its legend appear below.
منابع مشابه
Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles.
Hepatitis E virus (HEV) is the leading cause of enterically transmitted viral hepatitis globally. Of HEV's three ORFs, the function of ORF3 has remained elusive. Here, we demonstrate that via homophilic interactions ORF3 forms multimeric complexes associated with intracellular endoplasmic reticulum (ER)-derived membranes. HEV ORF3 shares several structural features with class I viroporins, and ...
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 114 24 شماره
صفحات -
تاریخ انتشار 2017